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What Is CBDV?

Reading Time 8 Minutes

What Is CBDV?

The hemp plant contains numerous cannabinoids– life-enhancing chemicals that interact with our bodies endocannabinoid system. Estimates range from 60 to over 140 of these different compounds, and as hemp research continues to develop, we are learning more and more about different cannabinoids every day.

One of these cannabinoids is cannabidivarin or CBDV for short. CBDV was first isolated in Germany in 1969, but research since then has been limited. This is true for many cannabinoids other than CBD. However, the research shows great promise for CBDV as a helpful compound that compliments other cannabinoids. 

CBDV Research

Chemically, we know that CBDV is structurally similar to CBD. It is a homologous molecule to CBD, which means that the basic structure is the same and the two molecules are differentiated by repeating elements such as side chains of different lengths or a peptide residue. In layman’s terms, this means that homologous molecules may have similar properties, and this does seem to be the case with CBD and CBDV. 

Biologically speaking, there are some major differences. CBD is relatively abundant, and commercial hemp strains may contain up to 30% CBD content. CBDV, however, isn’t even found in all strains of hemp. It isn’t even found in all hemp plants, and usually only makes up less than 1% of any hemp plant’s cannabinoid content. 

There are some African landrace strains of hemp that have up to 4% CBDV content, and some hemp breeders have experimented with plants and gotten results of up to 7% CBDV content. But 7% is still a long way from the quantities of CBD hemp plants can naturally produce. Also unlike CBD, CBDV is not easily produced in a lab from precursor compounds. 

Adding to the challenge of acquiring large quantities of CBDV is the fact that it is largely limited to landrace plants. Landrace hemp strains are naturally-growing hemp varieties that have not been crossbred with other strains. These plants must exist in relative isolation and have not been selected for favorable traits like commercially grown strains. CBDV is primarily found in Cannabis indica landrace plants originating in Africa, but it can also be found in somewhat elevated concentrations in indica landrace strains from Pakistan, India, and Mexico. 

While these plants can be farmed, they must be kept away from other plants to avoid the risk of cross-pollination. CBDV production is not a dominant characteristic in hemp plants, and it is a minor cannabinoid with an unknown botanical function. All of this means that there have been major stumbling blocks in researching CBDV. Even though it was first isolated in 1969, the first major research was not undertaken until 2012. There’s a lot that we don’t know yet about CBDV, but the research is very exciting.

Despite the difficulty in getting large quantities of CBDV, research has shown that it has promising effects on health. This is partially in part to how it interacts with the body. Unlike most cannabinoids, it does not react with the endocannabinoid system. Instead, it activates or desensitizes the transient receptor potential channels (TRP channels). The TRP channels play critical roles in managing our sensory systems and allow cells to detect changes in their environment. This system is linked to a number of sensory issues, as well as epilepsy and other types of seizures.

CBDV for Seizures

Beyond its anticonvulsant properties, studies have shown that there is a molecular component to the effectiveness of CBDV for epilepsy. One major study has shown that CBDV is effective in treating seizures from a variety of causes in rodent models. Additionally, CBDV treatment did not impact motor skills after recovery. This is a concern with some anti-seizure medications, and an anticonvulsant that does not cause impairments in motor skills shows potential for long-term use by chronic epilepsy patients. 

In further rodent trials, CBDV has even been shown to have an effect on epilepsy-related gene expression in brain tissues after seizures. The brain tissues’ responses were rapid and acute, and the CBDV seemed to interact directly with the brain instead of just the endocannabinoid system’s receptors. As in other trials, motor skills were also unaffected during post-seizure recovery. This indicates great promise for CBDV as a seizure medication. 

Drug trials for a CBDV-based seizure medication are already in progress. The pharmaceutical company GW Pharmaceuticals, manufacturers of the CBD-based Epidiolex, is currently recruiting for Stage III trials of their CBDV-based anti-convulsant for temporal lobe seizures. 

CBDV and Rett Syndrome

Rett Syndrome is caused by mutations on the X chromosome, it is characterized by the impairment of cognitive, sensory, emotional, motor, and autonomic function. Symptoms include repetitive hand movements, slower brain growth and intellectual disability. A rodent trial found that CBDV may contribute to reversing the deterioration and atrophy of the brain areas involved in Rett syndrome, and human trials demonstrated that a dose of 10 mg per day of CBDV a day significantly reduced seizures. 

Additionally, this trial showed that  Rett Syndrome patients who took CBDV also scored higher in areas including sociability, general health, brain weight, and hormone activity in the hippocampus (the part of the brain responsible for emotion and memory). This suggests that CBDV may also help with the non-seizure aspects of Rett Syndrome.

CBDV and Autism

CBDV has also been investigated for its therapeutic use for people on the autism spectrum. CBDV reacts with the brain’s excitation pathways, which are easily overstimulated and lead to repetitive behaviors that can interfere with an autistic person’s quality of life. CBDV is currently being trialed as a way to help autistic people manage their behavioral symptoms and mental health concerns. Additionally, autism and epilepsy frequently occur together, so a compound that can treat issues stemming from both may be beneficial to many people. 

CBDV also shows promise as a treatment for children with intellectual disabilities and may reduce the number of severe behavioral problems in these children, making it easier to keep them safe and care for them. CBDV is much gentler than sedatives, benzodiazepines, and other depressants. Additionally, it seems to have fewer short term and long term side effects and does not have a long term negative effect on gross motor skills, meaning that is likely a safer alternative to help these children.

Other Benefits of CBDV

Like many other cannabinoids, CBDV is effective at reducing nausea. This has been shown in studies using various animal models and is not surprising given that the first medically approved use for any cannabinoid was for nausea and vomiting. 

CBDV also shows promise as an acne treatment when used topically due to its anti-inflammatory nature. CBDV reduces the buildup of dead skin cells and lipids that form around inflamed skin, which is what causes acne breakouts. This is a topical application of CBDV and other key cannabinoids. 

How To Take CBDV

There is no psychoactive component to CBDV. It will not get you high or cause any kind of motor impairments. However, despite being totally legal in the United States, it can be difficult to find CBDV for sale. This is because landrace hemp strains are not the same things as commercial hemp, and so there are more restrictions around this kind of hemp. Furthermore, landraces typically contain a higher THC content than is allowed to be commercially grown in the United States. This means that acquiring pure therapeutic CBDV can be a challenge. 

We hold the CBDV that we offer here at Myriam’s Hemp to the same high standards of purity and quality that we hold all of our CBD products. You can rest assured that the CBDV we offer is made with natural, organic, high-quality ingredients. This includes our carrier oils, as well as the cannabinoids we offer. All of our products are lab tested and guaranteed to be free of sugars and other fillers.

Our CBDV tincture is best taken like all of our other tinctures. Simply use the dropper to place your dosage under your tongue, or mix it into a beverage if you prefer to take it that way. 

Buy CBDV at Myriam’s Hemp

At Myriam’s Hemp, our goal is to help you make the most of your cannabinoid experience. We believe in our products and want to help you take control of your health by offering premium hemp products, like CBD, CBG, CBN, CBDA, CBGA, and CBDV tinctures and topicals.

Our cannabinoid products are created with quality at the forefront, and we are constantly striving to enhance our offerings. Our products are designed with the goal of providing you with the relief you’re looking for and helping you manage your health without total reliance on traditional pharmaceuticals. Shop Myriam’s Hemp online and order your cannabinoid products today.

References

How To Get Rid of Brain Fog

Reading Time 4 Minutes

Brain fog is a chronic mental syndrome that combines cognitive fatigue, judgment issues, and memory impairment for an overall feeling of discomfort and disorientation. It has garnered attention recently as a symptom of COVID-19. This catch-all term has a number of contributing factors and can be tricky to understand. 

What Is Brain Fog?

Brain fog is the term used to describe a number of symptoms that all contribute to an overall uncomfortable feeling of being “spaced out” or mentally sluggish. Brain fog feels like a lack of mental clarity. When you’re dealing with it, it can be hard to focus or pay attention, and it makes it difficult for you to recall things.

Brain fog doesn’t necessarily hurt and it usually isn’t accompanied by pain. That said, brain fog can lead to additional symptoms, including prolonged or worsened sleep disorders, gastrointestinal dysfunction, and a decreased metabolism.

It can also have wide-ranging effects on your mental and emotional health. Brain fog can be confusing, frustrating, and upsetting. It can make problems seem much worse and make you feel like you’re losing control over small details, which is often quite distressing.

What Causes Brain Fog

There are lots of contributing factors to brain fog. It can be the result of numerous health conditions, including hormonal conditions and chronic health conditions. The following conditions are all associated with brain fog:

  • Insomnia
  • Stress
  • Dementia
  • Depression and other mental illnesses
  • Medication side effects
  • Thyroid disorders
  • Multiple sclerosis
  • Migraines
  • Cancer
  • Chronic inflammation
  • Head injuries
  • Nutrient deficiencies 
  • Chronic fatigue syndrome
  • Menopause
  • Viral infections, including COVID-19 

How Can CBD and CBDA Help With Brain Fog?

Because brain fog has so many different causes, we don’t know how many people suffer from it. However, neuroscientists point out that about 600 million people suffer from cognitive dysfunction. 

Cognitive dysfunction is a symptom that many people choose to address with CBD or CBDA. Studies have shown that CBD has therapeutic effects on many different areas of the brain, improving limbic system activity, cognitive pattern recognition, and overall performance of cognitive tasks and functions.

This is likely because of how CBD interacts with receptors in the body’s endocannabinoid system. The endocannabinoid system is a biological system that impacts your mood, pain sensation, mental function, and various other important bodily functions. CBDA also has impacts on your mood and mental function, but it works somewhat differently than CBD. 

CBDA interacts with our serotonin system, and through its interactions with this neurotransmitter, CBDA can have a powerful effect on the mind. CBDA is the precursor to CBD and is less well-known than CBD. Both CBD and CBDA can help fight brain fog, but they do so using different chemical receptors and signal mechanisms.

While less is known about everything that CBDA can do, CBD works to fight brain fog in a number of ways. Here are some of the ways that cannabinoids like CBD can directly impact brain fog.

Cannabinoids Reduce Inflammation

Research has shown that CBD can reduce inflammation throughout the body. Inflammation is linked directly to brain fog, especially in patients with post-COVID-19 neurological symptoms

Cannabinoids Promote Good Sleep

Sleep deprivation is a common root issue of brain fog, and CBD in particular has performed well in recent studies relating to sleep regulation.

Cannabinoids Reduce Anxiety

The use of CBD influences the activity in certain parts of your brain that are connected to stress, depression, and anxiety. The same is true of CBDA as it interacts with your serotonin system. A reduction in anxiety can improve your overall brain function, and research shows that CBD and CBDA are helpful for people with anxiety.

Boost Your CBD Tincture

More than half of all CBD users take the cannabinoid to address mental health concerns. A full-spectrum CBD tincture like our Daily 50 CBD Oil or our Premium CBDA Oil will engage the cannabinoid receptors in your brain and may lead to improved cognitive function, including improved memory, clarity, and focus.

If you want to take CBD or CBDA specifically to address the “fuzzy” feelings of brain fog, you can choose to add the Focus Terpene Boost blend to any of our tinctures. This is a proprietary blend of specific terpenes that are geared to enhance your experience by improving focus, clarity, and cognitive function. Simply scroll down before you add your tincture to your shopping cart and choose the Focus Terpene Boost– it’s that easy.

Buy CBD and CBDA at Myriam’s Hemp

At Myriam’s Hemp, we want to help you improve your life and make the most of your cannabinoid experience. Our goal is to provide hope to those who are suffering from conditions that can have a significantly negative impact on everyday life. Our cannabinoid tinctures and topicals are created with quality ingredients that may provide you with the relief you’re looking for. Shop Myriam’s Hemp online and order your cannabinoid products today.

CBG for Anxiety & Mental Health

Reading Time 5 Minutes

Cannabis and hemp possess a virtually infinite potential for the world of health and wellness and have already proven to be both physically and psychologically beneficial by amateur and anecdotal experience and scientific investigation. Cannabigerolic acid—also known as CBGA—is one of the many derivative byproducts of hemp, and emerging studies are beginning to highlight its amazing benefits in the realm of mental health.

What are CBGA and CBG?

Before we dig into how CBGA and CBG can help your brain, let’s take a quick look at what they are and how they work.

Both CBG and CBGA are cannabinoids, and they share this classification with better-known cannabis derivatives, like THC and CBD. In its acidic form, CBGA (sometimes written as CBG-A) breaks down into one of the many cannabinoids. In some instances, it may break down into CBG.

Right now, CBG research is in its infancy. Compared to many of the other cannabinoids, it hasn’t seen as much scientific or social interest. However, with technology and efforts surrounding cannabis legalization growing daily, more studies are being conducted on CBGA and CBG than ever before.

CBG works by binding to both CB1 and CB2 cannabinoid receptors in the brain, nervous system, and immune system, providing full-body benefits and protection. Once in your body, CBG helps to increase the production of anandamide. Anandamide is a neurotransmitter that helps with pain regulation, sleep cycles, appetite, and motivation/mood.

Because this cannabinoid is lesser-known and less studied, CBG is more difficult to find in the marketplace. While you may find CBG for sale at a local dispensary, it’s not a common item to find.

Fortunately, Myriam’s Premium Hemp Products online store is always open, and we stock plenty of CBG oils and tinctures. Keep reading to explore more about CBG

Does CBG Make You High?

No! CBG does not make you high. 

CBG is a nonintoxicating cannabinoid, unlike the more popular ones like THC or THCA. Taking CBG does not impact motor function or perception, and is safe to take if you prefer to avoid intoxicants.

CBG for Mental Health

Aside from its many physical benefits, CBG has been shown to improve mental health. Its use has been reported to alleviate a variety of psychiatric symptoms, and respondents in one study even lauded CBG as a more effective treatment plan than their conventional medicinal routine.

CBG & Anxiety

Anxiety is a huge problem in the modern world. We are constantly surrounded by stimulation, and our stress will often morph into anxiety. While there are plenty of treatments available, many of them often cause negative side effects, or just don’t give you the relief you want. Fortunately, CBG is different, and can safely be taken alongside other methods of alleviating anxiety.

Does CBG Work for Anxiety?

CBG has been proven to alleviate symptoms of anxiety, and studies suggest that it does so without the negative effects of many standard pharmaceuticals.

While we don’t know exactly why this is, we do know that CBG promotes muscle relaxation. Paired with its ability to promote dopamine production, CBG mimics the way we naturally deal with anxiety.

Think of it as a massage for your mind. When you’re feeling stressed and anxious, you’ll often find a spot to relax and unwind. When you’re lounging on your sofa, you’re relaxing your muscles. At the same time, your brain is releasing plenty of dopamine, which is responsible for happy thoughts and positive feelings.

CBG for Depression

Thanks to the release of dopamine, CBG also doubles as a potent ward against depression.

Many of the physical effects of CBG are also linked to common causes of depression. One of the most common is chronic pain, which is often relieved by CBG’s anti-inflammatory properties.

For individuals with other ailments, such as AIDS or cancer, CBG is also shown to stimulate appetites. As a result, many users report feeling more energized, as they are naturally encouraged to eat a hearty meal after using CBG.

Where Can I Get CBG?

We’ve already mentioned it, but let’s look a little deeper into the issue of availability. Because CBG is not one of the more popular cannabinoids, it tends to be harder to find.

At Myriam’s Premium Help Products, we always stock high-quality CBG products. We’re also proud to feature two amazing CBG products, and you can easily purchase them directly from us.

CBG 600

Myriam’s Hope Hemp always guarantees that your product will be fantastic, and that’s why we have proprietary blends – we want formulas we can trust. One of these is CBG 600. This mix contains 600 mg of CBG per ounce, which means it packs a real punch! All of our CBG products are full-spectrum, which means you aren’t missing out on any of the essential components of this beneficial cannabinoid. If you are interested in adding additional terpenes to boost flavor and wellness benefits, we can customize any CBG order.

CBG 1200

In addition to our classic CBG 600 tincture, Myriam’s Hope Hemp also offers our NEW CBG 1200 blend. This tincture doubles the amount of active CBG to 1,200 mg per ounce, and it still has the flexibility of our classic CBG 600. Remember, adding additional terpenes can give you a custom blend with added benefits just for your particular needs.

The Myriam’s Hope Hemp Difference

At Myriam’s Hope Hemp, all of our proprietary products are made in the USA. Each tincture, oil, and bottle is rigorously tested to ensure maximum efficacy and absorption. Everything is sugar-free and vegan friendly, which means that everyone can get the all-natural relief that they need.

In addition to our fantastic tinctures, Myriam’s Hope Hemp also offers premium CBD-based topical treatments. If you’re looking for a new way to treat the woes of modern life, then check us out! We’re more than happy to help you find the perfect blend.

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