People seek out cannabis products for any number of reasons. It could be a natural part of their holistic wellness practices, as a supplement to their treatments, or to create a sense of health and wellness, cannabinoid effects are versatile. At Myriam’s Hemp, we believe that hemp and its cannabinoids can have a helpful effect on many people. We’ve created a line of products that make use of these compounds and are easy to include in your day-to-day life. On our blog, you’ll find a variety of resources and insights into cannabinoids, their uses, and their effects. From articles to videos and graphics, there’s a lot to enjoy on our blog.

Study Reports Preliminary Results of CBD Liver Safety

Results of CBD Liver Safety Study

Study Reports Preliminary Results of CBD Liver Safety

A patient-centered clinical trials company called ValidCare has recently concluded a 7-month study of the effects of CBD use on the liver. Overall, their findings have been advantageous to the consumer as their “investigators report to FDA no evidence of liver toxicity in the 839 adults consuming oral CBD”. This study was in response to the FDA’s request for science-based data to help determine the appropriate regulations for hemp derived CBD products.

The 7 Month Testing Process

With the help of twelve CBD product companies and 839 participants, ValidCare carried out a 7-month study of the effects of CBD on the liver. The study began in August 2020 and came to a close in February 2021. It may seem like conducting a study during the pandemic would prove to be problematic, but the “use of ValidCare’s decentralized clinical research platform and partnership with national laboratories enabled participants and principal investigators to successfully complete this first cohort” and the FDA and brands involved were delivered results within six weeks.

The main purpose of this 7-month study was to “observe any potential liver effects in adults ingesting oral forms of hemp derived CBD for a minimum of 60 days”. To successfully complete this study, ValidCare needed a minimum of 681 participants, and with the help of the participating product companies, they were able to have over 830 participants complete the study.

ValidCare’s Findings

Over the course of the 7-months ValidCare has found “no evidence of liver disease in the 839 participants and no increase in the prevalence of elevated liver function tests when compared to a population with a similar incidence of medical conditions”. Three participants were reported to have three times the normal levels of the liver enzyme ALT, but they were all taking prescription medications that are known to elevate liver enzymes.

The results of the study have been encouraging as it provides sufficient science-based data to the FDA, for them to take action on safety regulations for CBD in the future. That being said, this 7-month study has only been the first cohort, and ValidCare will continue to analyze real-world data and perform a second cohort to add to the statistical certainty for liver safety. ValidCare is “excited for [their] principal investigators to continue, expand and report out on this foundational work in the next few months. Once completed, safety results of this study will be shared with participation brands and the FDA.”

Myriam's Hemp CBD

At Myriam’s Hemp, our goal is to provide valuable information and resources about CBD to consumers and customers alike. In addition, we remain committed to that staying aware of new developments and studies performed within the industry and providing you with resources so you can find the solutions that best work for you.

If you’re looking for high quality CBD products, you can count on Myriam’s Hemp to provide you with reliable CBD tinctures and balms that are free from chemicals and fillers. We only use all natural ingredients and make our products as accessible as possible to consumers by keeping them free of wheat, sugar, and animal products.

Purchase your CBD products from Myriam’s Hemp online today or reach out to a member of our dedicated team to determine which CBD products are right for you!

CBD as Potential Treatment for COVID-19

CBD as Potential Treatment for COVID-19

CBD as Potential Treatment for COVID-19

Recently, a study was conducted by a team of researchers in Illinois at the Rosner Lab at the University of Chicago to analyze if cannabidiol could be a potential treatment for COVID-19. In March 2021 Rosner Lab released their latest findings with evidence demonstrating the inhibiting effect of CBD on the replication of the SARS-CoV-2 virus. This study highlights CBD and its active metabolite as potential preventative agents and therapeutic treatments for SARS-CoV-2 in the early stages of infection.

Why Was This Study Conducted?

With a wide and rapid spread of SARS-CoV-2 across the globe, researchers began to look for alternative ways to reduce the spread and effects of COVID-19. Colleagues at Rosner Lab say that the fact that the virus is still spreading even with the rollout of vaccines highlights the need for alternative approaches. This is especially true for populations with limited access to vaccines.

What Did the Study Involve?

The SARS-CoV-2 virus enters host cells via the binding of a surface viral protein to the human host cell receptor ‘angiotensin-converting enzyme 2 (ACE-2). To test the effect of CBD on SARS-CoV-2 replication, researchers at Rosner Lab pretreated A549 human lung carcinoma cells expressing exogenous human ACE-2 receptors for 2 hours with CBD, before infecting them with SARS-CoV-2. Then after 48 hours had passed, they monitored and analyzed the cells to see if the replication of the SARS-CoV-2 had been inhibited.

The Findings

Overall, the researchers at Rosner Lab have concluded that they have evidence that CBD inhibits the replication of the SARS-CoV-2 virus. In addition to that, they have also released some key findings broken down in simpler terms for the public to understand:

  • After viral entry, CBD acts to block virus replication.
  • CBD has the potential to not only act as an antiviral agent in the early stages of infection but also protect the host against an overactive immune system during the late stages.
  • CBD inhibiting replication of at least one other coronavirus raises the possibility that it may also inhibit other human coronaviruses that could arise in the future.
  • 7-OH-CBD (a metabolite of CBD) is an effective inhibitor of SARS-CoV-2.
  • Analysis of participants taking FDA-approved CBD showed up to ten times a decreased risk of SARS-CoV-2 infection compared to a set of control participants.

Although these findings represent a significant process in the alternative treatment of COVID-19, there are still “several issues that require close examination before CBD can be considered or even explored as a therapeutic for COVID-19”. For example, it appears that the presence of THC may counteract the antiviral efficacy of CBD. And of course, other concerns would need to be addressed, such as the means of administration like smoking or vaping that could potentially cause lung damage. In short, further studies would be needed to determine optimal methods of delivery, and clinical trials should be performed to test the promise of CBD as a therapeutic for SARS-CoV-2.

Myriam's Hemp CBD

We are proud to serve an ever-growing community of families just like ours who keep coming back to Myriam’s Hemp CBD oil and CBG oil for the relief they can count on. We are also committed to providing our customers with quality resources and studies in the industry, so you have all the information needed to find solutions that fit your life.

You can count on Myriam’s Hemp to provide you with high quality CBD products that are free from wheat, sugar, animal products, chemicals, and fillers. Purchase your CBD oil or CBG oil from us today or reach out to someone on our team to determine which products are right for you!

What is the Entourage Effect in CBD?

What is the Entourage Effect in CBD?

What is the Entourage Effect in CBD?

Many might think that cannabis comprises just two natural ingredients that provide an abundance of health benefits – THC and CBD – but there are various other chemical compounds (phytocannabinoids) that are thought to aid in the delivery of the plant’s natural advantages. These other compounds might not make it onto the webpages of most dispensaries, news agencies, or social media, but as we discover more about the makeup of the cannabis plant, it begs the question: What is the entourage effect? The additional compounds found in cannabis are essential contributors that work together with THC and CBD to provide the effects that many patients and customers seek. This combination of phytocannabinoids that includes CBG, CBC, CBN, and various others has been referred to as the CBD entourage effect, and we believe that it’s important to take a closer look at what that means for you.

What is the Entourage Effect in CBD?

How Does it Work?

The entourage effect occurs as cannabis is smoked or vaporized and the various compounds mix together to provide collaborative benefits. Studies have found that CBD works best when activated by a small amount of THC, and numerous CBD products today contain trace amounts of THC as a result. But while not yet proven, doctors and cannabis experts have developed the theory of the CBD entourage effect based on a combination of research and controlled studies. The research available tells us that combining both terpenes and phytocannabinoids may provide enhanced benefits for the relief of different ailments such as pain, anxiety, inflammation, cancer, epilepsy, and even fungal infections when compared to CBD or THC on their own.

More research is definitely needed, but there is a strong belief that the CBD entourage effect is real, and it could open up a number of doors in terms of alternative healthcare. Many who use cannabis for its known medical benefits prefer flower as opposed to oils and extracts for this reason, as the flower is the most natural and unaltered form of the plant.

Potential Benefits of the Entourage Effect

Knowing what we do about the entourage effect in CBD, it could mean that cannabis is even more beneficial than we ever believed. We would have the ability to pair specific phytocannabinoids together to achieve a particular desired effect, such as for chronic pain relief, anxiety, or even cancer prevention. Again, these are still just theories for the time being, but other benefits could potentially include:

Increased memory function by pairing the pinene terpene with THC

Addiction treatment by pairing CBD with caryophyllene

Reduced anxiety by pairing the terpene limonene with CBD

Advanced sedation by pairing THC with CBN

Currently, there are several cannabis forms available such as oils, tinctures, and other edibles that are labeled as “full spectrum”. This means that they contain pure cannabis oil extracted from plants using advanced technology such as supercritical CO2 extraction machines. These products are intended to contain all of the phytocannabinoids that cannabis offers including THC, CBN, CBD, CBG, terpenes, and hundreds of other compounds that deliver the entourage effect and all of the benefits that go along with it.

When these products are altered to provide customers with different effects, they become labeled as broad-spectrum instead – cannabis products with the THC removed, for example. The advantage of isolating specific compounds, however, is that we can pair intentionally to produce specific effects that can provide medically beneficial results. With further research and development, the possibilities could be virtually endless.

If you’re looking to experience the benefits of the entourage effect in CBD, Myriam’s Hemp is here to help you make an educated choice. We’re committed to providing detailed information surrounding medicinal cannabis as well as the CBD entourage effect in the hope that you can find the relief you need to live a happy, healthy life. Visit our product page to purchase CBD today.

Which Cannabinoid is Right for You?

Which Cannabinoid is Right for You?

Which Cannabinoid is Right for You?

Cannabinoids are the naturally occurring chemical compounds found in the cannabis plant, many of which are separated to create various products that offer different intended effects. Regardless of what the desired end product is, manufacturers will extract these cannabinoids carefully to preserve their natural benefits so that their full potential can be realized. While there are many different cannabinoids that we know of, some are more well-known than others, such as THC and CBD. Each offers different characteristics and potency levels, and they react with the brain in different ways to achieve specific outcomes.

Which Cannabinoid is Right for You?

What are Differences in Cannabinoids?

While most cannabinoids have demonstrated benefits such as pain relief, they react differently to receptors in the brain. Let’s dive into some of the most common cannabinoids, their effects, and their potential benefits.

THC – Tetrahydrocannabinol. One of the only cannabinoids that will produce a high, THC is also the cannabinoid that is most abundant in marijuana and it has been found to be effective in relieving or reducing pain in some cases, as well as promoting a healthy appetite.

CBD – Cannabidiol. CBD is frequently used for medicinal purposes because it does not produce the same high as THC. However, it can be combined with THC to amplify the effects. Continued use of CBD has demonstrated the potential to improve numerous negative health conditions, such as reduced feelings of stress and better sleep.

CBDA – Cannabidolic Acid. CBDA is the raw acidic form which converts into CBD when it is dried and heated. In its raw acidic form, there have been reports of it potentially being more potent than CBD in smaller doses for anti-inflammatory purposes. This may be useful when used as a remedy for muscle pain or inflammation after an injury or infection.

CBG – Cannabigerol. CBG is becoming more popular among researchers and medical professionals. It has become a choice for alternative cancer fighting strategies as it may decrease the number of bacteria that can grow. If effective, this could stunt tumor and cancer cells.

CBN – Cannabinol. CBN occurs when THC oxidizes and loses its intoxicating effects. This cannabinoid may be able to help with concerns surrounding pain, inflammation, sleep disorders, and appetite stimulation.

Choosing the Right Cannabinoid

Determining the right cannabinoid depends on the ailment that you’re trying to get a handle on. Most cannabinoids have been found to deal with pain symptoms, though CBD has proven to be a popular choice for most people looking to manage regular pain or inflammatory problems such as arthritis. CBD is also readily available in numerous forms and offers a good starting point to begin your healing journey. At Myriam’s Hemp, we carry various options for CBD, CBDA, CBG, and CBN. If you have questions, we’ll happily take the time to help you determine which cannabinoid will offer the right solutions for your individual needs.

Buy Cannabinoid Oil Online at Myriam’s Hemp

All of the products offered at Myriam’s Hemp are made with 100% natural ingredients and are specially formulated for maximum absorption and efficiency. They don’t contain any sugar or wheat and are vegan friendly making them a viable option for most people. Each product contains less than 0.3% THC and focuses instead on the known health benefits of other cannabinoids that can help to promote the relief of a myriad of different medical ailments. Our goal is to show you the change that premium hemp products can exact in your life, and we do that by producing our products with quality at the forefront of our minds. Many of our customers use cannabinoids such as CBD for medical purposes, and you can, too. Shop our available products and purchase CBD or other cannabinoid products online today.

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