When it comes to finding the right CBD products for your healthy lifestyle, there are a lot to choose from. From pills to tinctures, creams, salves, and many more, finding a high-quality hemp product is easier said than done. Fortunately, we’ve made this choice easy for you. At Myriam’s Hemp, we’re involved in every step of creating our products. From growing the hemp to extracting our full-spectrum CBD and finally packaging and labeling it, you can trust our products to be the best available. You’ll find a great wealth of information about CBD products on our blog. Check back often for new posts!

Myriams Hemp CBGA

What Is CBGA?

What Is CBGA?

The cannabis plant is full of life-enhancing compounds called cannabinoids, and no one knows precisely how many there are; the number may be as high as over 140! We are still discovering more about cannabinoids and their uses every day.

One of these cannabinoids is cannabigerol acid, or CBGA. This non-psychoactive cannabinoid compound has many valuable properties and is one of the few cannabinoids that has received substantial scientific investigation. Here, we cover what you need to know about CBGA and share what we know about this unique compound.

CBGA’s Botanical Function

When a hemp plant starts growing, it only produces one cannabinoid: CBGA. All of the others are derived from this cannabinoid. CBGA is a precursor compound produced in the hemp plant’s trichomes. In the plant, it triggers targeted cell necrosis in the leaves, essentially telling them when to die so that the plant can put more energy towards the flower.

As a precursor compound, CBGA is a foundational compound of the cannabis flower’s other major compounds as a precursor compound. This means that it is at the top of the chain reaction that produces the three major cannabinoid lines: THCA (tetrahydrocannabinolic acid), CBDA (cannabidiolic acid), and CBCA (cannabichromenic acid). These, in turn, become THC, CBD, and CBC. CBGA can also convert to CBG, but in most strains of cannabis, CBGA converts into THC or CBD. This has made CBGA extremely important in hemp research!

Most of what we know about CBGA comes from research on the compounds it turns into. In the 1960s, Israeli researchers isolated CBG; in the 1990s, Japanese researchers discovered that it came from CBGA. Since then, most CBGA research has focused on how to convert it to other cannabinoid compounds. Primarily, this involves synthesizing THCA (and often subsequently THC) for research and pharmaceutical purposes.

The ability to synthesize CBGA is important because it is difficult to keep intact. While CBGA is found in large quantities in young plants, exposure to heat immediately starts the chain reaction that converts it to another molecule. Additionally, most of the CBGA a cannabis plant makes over its life becomes THC or another compound through the plant’s own biological processes.

This has led to advanced research in biosynthesis, and as recently as 2019, researchers discovered how to synthesize CBGA and other cannabinoids in yeast. This means that research on this compound and what it can do will be much easier going forward, as the researchers are not limited to harvesting the minute quantities that the hemp plant naturally produces.

How Does CBGA Work?

CBGA, like all cannabinoids, acts by binding to the body’s endocannabinoid system. This system of receptors is dispersed all throughout the body and only activates in the presence of cannabinoids. When CBGA is converted to CBG, it binds to CB1 receptors that act directly on the brain and nervous system without having a psychoactive effect. CBGA on its own, binds to CB2 receptors, which are involved in the immune system and gastrointestinal system.

What Can CBGA Do For You?

Most of the existing research on CBGA focuses on its transformation to THCA, CBDA, or other cannabinoids. This means that most research on the benefits of CBGA is connected to its use after that transformation. But as we learn more about CBGA, researchers are finding that it has many potential benefits of its own.

COVID-19 Prevention

One of the most recent findings is that CBGA, along with CBDA, may successfully prevent COVID-19 transmission and infection. The cannabinoids prevent infection by binding to the SARS-COV-2 spike protein. This prevents it from entering the cell and reduces the chance of infection. It also shows promise in preventing and treating new variants of COVID-19. While these are preliminary findings and substantial additional research and testing are necessary before truly being considered a treatment for COVID-19, this research is very promising.

Cardiovascular Disease

In vitro studies of CBGA have found that the compound significantly inhibits the enzyme aldose reductase. This enzyme is a major contributor to oxidative stress that leads to heart problems, as well as other negative effects on the body. This research is valuable because synthetic inhibitor drugs have severe negative side effects for many patients. A plant-derived inhibitor drug based on CBGA could help millions of people who suffer from cardiovascular disease or cardiovascular symptoms of metabolic diseases like diabetes.

Inflammation Relief

Rodent studies show that CBGA has a powerful positive effect on some of the metabolic receptors that trigger inflammation. Additionally, CBGA can also inhibit the action of cyclooxygenase enzymes, more commonly known as COX inhibitors. COX inhibitors reduce the production of prostaglandins, which are chemicals that the body produces to help reduce inflammation. By inhibiting the inhibitors, CBGA helps reduce inflammation and pain in the body.

Seizure Treatment

CBGA is a potentially powerful anticonvulsant treatment for seizure disorders like epilepsy. Cannabis has been used to treat epilepsy for thousands of years, and today’s modern hemp-derived epilepsy treatments contain little to no THC. Instead, other cannabinoids are the primary focus. The best known and best understood is CBD, but minor cannabinoids like CBGA show a lot of promise in anticonvulsant research. CBGA has been found to react with numerous seizure-related receptors and is highly effective in certain induced seizure conditions in mice. This could translate into support for an increase in CBGA as a treatment for seizures in humans as well.

Metabolic Disease

CBGA may also help patients with metabolic disorders due to its reaction with peroxisome proliferator-activated receptors (PPARs) that regulate metabolism. When PPARs do not function properly, people accumulate lipids excessively and develop metabolic diseases like diabetes and high levels of cholesterol and triglycerides. One study shows that cannabinoid acids like CBGA are PPAR agonists, which means that they can help regulate PPAR expression. Another study found that cannabinoids positively regulate PPAR-associated genes that control lipid metabolism.

Neuroprotection

In addition to regulating PPAR activity, CBGA also has other regulatory properties. One of these is its ability to protect against the neurodegenerative effects of Huntington’s Disease. In this study, it was found that acidic precursors like CBGA are demonstrably more effective than their
subsequent cannabinoids. This was seen in both cell line studies and rodent studies and is a very promising line of research.

Additionally, CBGA may protect against the neurotoxicity that stems from the stress of oxidation particles, hydrogen peroxide (H2O2), and rotenone, which causes mitochondrial dysfunction. In this in vitro study, a high concentration of CBGA dramatically reduced the rotenone-induced neurotoxicity. CBGA is also shown to prevent the formation of superoxide radicals, which eventually reduces oxidative conditions that lead to neural degeneration. In other words, it’s a powerful antioxidant that can help protect your cognitive function as you age.

Colorectal Cancer Treatment

While it is important to note that the research is in very early stages, CBGA may one day be a vital treatment for patients with colorectal cancer. Colorectal cancer is the third most common cancer and is the fourth leading cause of cancer-related death, so additional therapies and treatments will save many lives. As we mentioned previously, CBGA has cytotoxic or cell-killing effects that tell the plant to redirect energy to the flower instead of the leaves. Its primary job is to tell cells when to die. The effect may not be limited to cells in the hemp plant.

Research shows that these cytotoxic effects also have an effect on colon cancer cells. In experiments on colon cancer cell lines, CBGA killed colon cancer cells, sped up early cancer cell death, and stopped the cancer cell cycle. Additionally, the research is encouraging in regards to preventing the growth and spread of cancerous polyps, which grow into potentially lethal carcinomas.

How To Get CBGA

CBGA is found in all varieties of the hemp plant, including hemp plants that produce low amounts of THC. This means that it’s legal in all 50 states! While CBGA is not mentioned specifically by name in the 2018 Farm Bill or other cannabis laws, it can be derived from hemp plants that contain virtually no THC. Additionally, CBGA is not psychoactive, so it is generally treated with the same considerations as other non-psychoactive cannabinoids. Since CBGA is completely legal, it can be found in a number of locations. Hemp shops and CBD retailers will likely carry CBGA products, as will shops that cater to specialty health concerns and wellness, such as Myriam’s Hemp. Be sure to specify that you are looking for CBGA and not the more commonly-known CBG, as the two have different effects!

How To Take CBGA

If you’re interested in trying CBGA, there are several different ways you can consume it. Remember, CBGA is very susceptible to heat, and as soon as it is exposed to heat, it begins the reaction that changes it into another cannabinoid, typically CBG. That means you probably won’t have much luck consuming it through any leaf-based method, as most of those involve heat.

Even if you keep the temperature low, the drying and curing process itself can also have an effect on the amount of CBGA available to consume. Smoking, vaping, or baking into food will transform your CBGA into CBG, so those routes just are not ideal if you want the full CBGA benefits. And while CBG is helpful in and of itself, it provides different benefits than CBGA!

Tinctures, on the other hand, are a much more reliable way to take CBGA. CBGA can be synthesized in a lab and distilled into a tincture that you can take just like any other cannabinoid tincture. When you choose a CBGA tincture, you should make sure to choose one from a company that is transparent about lab testing and one that uses all-natural ingredients for your safety.

You should also know that cannabinoid precursors, including CBGA, are not present in all types of tinctures. A CBG tincture is not going to contain CBGA. A broad or full spectrum tincture may contain CBGA, along with many other cannabinoids, to enhance the entourage effect.

If you’re looking for specific CBGA responses, however, your best bet is to choose a full spectrum CBGA tincture with a higher concentration of CBGA compared to the other cannabinoids to allow the cannabinoid to shine through. In the coming weeks, we will be releasing our own all-natural CBGA tincture for healthful relief.

Buy CBGA at Myriam’s Hemp

At Myriam’s Hemp, our goal is to share useful information that will help you make the most of your cannabinoid experience. We believe in our products and want to help you take control of your health by offering premium hemp products. We provide hope to those who are suffering from diseases that can have a significantly negative impact on everyday life.

Our cannabinoid products are created with quality at the forefront, and we are constantly striving to enhance our offerings. Our online store features a variety of CBD, CBG, CBN, CBDA, and soon, CBGA products that may provide you with the relief you’re looking for and help you to manage your health without total reliance on traditional pharmaceuticals. Shop Myriam’s Hemp online and order your cannabinoid products today.

References

Can CBDA Help Prevent COVID-19? A New Study Says YES!

Can CBDA Help Prevent COVID-19? A New Study Says YES!

It’s common knowledge that CBD from hemp can help lower inflammation and strengthen your immune system overall. A new study done by Oregon State University researchers has found that CBDA, a parent molecule to CBD, may actually help in the prevention of the COVID-19 virus and its variants.

How Does Cannabis Help with COVID? What the Study Says

Researchers have already known for a while now what CBDA can do to alleviate inflammation, digestion, and much more (see the last section in this article for more information about that). What an exciting new study at Oregon State University found out recently, however, was what this CBD precursor may be able to do to protect against the virus that produces COVID-19 as well.

A team of scientists at the Linus Pauling Institute at Oregon State University in Corvallis, OR, in partnership with investigators at Oregon Health & Science University in Portland, recently discovered that both CBDA (cannabidiolic acid) and CBGA (cannabigerolic acid) have the ability bind to SARS-COV-2 spike protein. Both of these cannabinoids are found in hemp variations of cannabis.

This is a huge discovery because it means that CBDA and CBGA may have the ability to prevent the spike protein from entering cells and causing COVID-19. The Oregon State University report was published January 10th, 2022 in the Journal of Natural Products. (1)

Can CBDA Also Protect Against New COVID Variants?

According to the University of Oregon researchers, the answer could also be yes.

Dr. Richard Van Breeman, principal investigator at the Linus Pauling Institute and professor of chemistry at Oregon State, commented in a recent interview that CBDA and CBGA may be effective against emerging COVID variants as well. Two variants mentioned in the study include “B.1.17” (Alpha variant) and “B.1.351” (Beta variant).

Both Alpha and Beta are currently classified as “VBM” (Variants Being Monitored) by the U.S. Centers for Disease Control. (2) According to Yale University, the Alpha variant was first discovered in the UK in November 2020. Until the emergence of Delta, it was the predominant variant amongst infected individuals in the US.

Also, according to Yale, the Beta variant was discovered in South Africa at the end of 2020. So far it has not been as widespread. Experts state, however, that it is about 50% more contagious than the original virus and potentially 20% more contagious than the Alpha variant. (3)

“Orally bioavailable and with a long history of safe human use, these cannabinoids [CBDA and CBGA], isolated or in hemp extracts, have the potential to prevent as well as treat infection by SARS-CoV-2,” the report authors state.

More on CBDA

A lot goes into the creation of the cannabinoids most people are familiar with that are found in both medical marijuana and hemp. CBDA and CBGA, which are major players in the formation of CBD, CBG, and CBN are considered “parent molecules”. In other words, those cannabinoids are created first and then CBD and other cannabinoids eventually emerge from them.

 CBDA specifically is considered a powerful healing substance in its own right. That being said, CBDA actually works much differently than CBD and THC cannabinoids in the body. The main difference is that CBDA does not interact much with the endocannabinoid system. It does not bind with CB1 nor CB2 receptors. Instead, it interacts with receptor sites for certain brain and nervous-system precursors such as 5-HT. 5-HT is a chemical needed for the production of serotonin. CBDA also interacts and influences key enzymes to produce its healing effects.

CBDA also affects the production of serotonin itself and the way this hormone interacts in the body. Serotonin is mostly known as a neurologically influential hormone that produces feelings of happiness and fulfillment.

Serotonin does a lot more than this in the body overall, however. It is a key hormonal substance for emotional regulation and the proper functioning of motor skills. It also influences digestion, sleep cycles, and cardiovascular health. According to a 2017 study conducted at the University of Freiburg in Germany, serotonin also plays a part in cytokine and T cell production in the immune system, amongst other things. (4)

Besides being a potential preventative against various strains of COVID, research into CBDA has found that it can also be beneficial for depression symptoms, digestive issues such as nausea and vomiting, brain and nervous system conditions, such as seizures, and for lowering inflammation overall. (5) (6)

How Can I Obtain CBDA?

Oregon State University researchers present hopeful research for the possible natural prevention of this dreadful virus that has changed the way the whole world functions. Recent research has found that CBDA in particular is more readily absorbed into the bloodstream and body than regular CBD. What’s more, both CBDA and CBGA are found in hemp. This means that they are legally available in most regions of the US.

You should know, however, that these cannabinoid precursors will not be found in regular CBD products. CBDA, however, can be purchased as super high-quality full-spectrum CBDA oil or as a CBD/CBDA blend right here at Myriam’s Premium Hemp Products!

References:

CBD Gummies vs CBD Oil

CBD Gummies vs. CBD Oil

CBD Gummies vs. CBD Oil

Before diving into the differences between CBD gummies vs CBD oil, it may be helpful to know more about CBD itself. Cannabidiol (CBD) is extracted from the hemp plant, which, unlike cannabis,contains only trace amounts of the psychoactive cannabinoid tetrahydrocannabinol (THC). There are many products on the market that are infused with CBD from vapes, lotions, and oils to chocolate, tarts, and gummies, that have been crafted to provide consumers with the associated benefits of CBD.

Out of all the CBD products available, the two most popular products are CBD oils and CBD gummies –probably because both are discrete. Oil is simple to take while you’re on a quick break, and gummies are easy to stash away in your purse, backpack, or briefcase. We’ll look at the additional benefits and differences of these two products so you can determine which is best for you.

CBD Oil

Sometimes referred to as a CBD tincture, CBD oil is an oil that contains a cannabidiol (CBD) extract. The most effective way to take CBD oils is by placing drops of the oil underneath your tongue and letting it absorb into your bloodstream. This method is called the sublingual method, and it enables the CBD to get to work very quickly because it doesn’t need to travel through your digestive system first, and effects can be felt in as little as 15 minutes.

CBD oil tends to have a distinct hemp flavor that some describe as bitter. If you would prefer to mask the flavor, CBD oils can easily be mixed into a variety of drinks and foods such as coffee, tea, smoothies, and soups. Ingesting CBD oil instead of placing it under the tongue may delay its absorption into your bloodstream. Whether you choose to take your CBD oil sublingually or orally, it’s important to remember that as it is a natural product, it is important to store your CBD oil properly to prolong the life.

CBD Gummies

CBD gummies have become increasingly popular with consumers who are looking for a fun and tasty way to take a controlled dose of CBD. Gummies are usually infused with a CBD isolate which is pure CBD without any of the other naturally occurring hemp elements, making it perfect for those who want to avoid THC in its entirety. As expected, CBD gummies are enjoyed orally and therefore provide a delayed release into your bloodstream. Although CBD gummies don’t provide a quick response, they do last a bit longer as they are metabolized slower than an oil taken sublingually. Anyone with a sweet tooth will be reaching for CBD gummies over CBD oil, and with a range of fruity and tart flavors, they are a fan favorite.

CBD Strength and Dosing

Regardless of which product strikes your fancy, you should be aware of the strength of the product and the appropriate dosage. Droppers of oil can allow you to have more control over your dosage while gummies can provide you with more control over CBD levels. Either way, allow time for your body to digest and adjust before taking more CBD.

Choose What Works for You

Even with their differences, oils and gummies are both great products that allow consumers to enjoy the benefits of CBD. In the end, it is up to you to determine which product best suits you and your needs. If you need help choosing the right product, Myriam’s Hemp is here to help you explore your options for better relief. Myriam’s Hemp CBD Gummies are coming soon!

Valentine’s Day CBD Gift Guide

Valentine’s Day CBD Gift Guide

If you’ve been frantically searching for a unique and unexpected gift that won’t leave you clutching your wallet in despair, we recommend checking out CBD for Valentine’s Day this year. A beacon of health and wellness, CBD gifts are a great option for everyone. To help you in your search for the perfect gift, Myriam’s Hemp has created a Valentine’s Day Gift Guide so that you can determine the most ideal CBD gift for your loved one.

Valentine's Day CBD Gift Guide

Finding the Perfect Gift

In the past, purchasing CBD for Valentine’s Day may have been completely out of the question. But now, times have changed drastically, giving couples and lovebugs the opportunity to dote on one another in a unique way. Depending on what your better half struggles with on a day-to-day basis, they may benefit from a particular product – we have several to choose from:

If your sweetheart has been experiencing muscle aches, inflammation, or skin issues, our CBD Balm is an excellent choice. It also doubles as a great addition for massages so be prepared to turn this CBD gift for Valentine’s Day into the ultimate gift.

Raise your loved one’s spirits with full spectrum hemp oil. Many of our customers suffering from chronic pain or high levels of stress, choose to purchase our Daily 50 CBD or CBG Oil which helps them to alleviate the troubles of the day.

One of the most common issues and causes for pain is inflammation. If your better half has been struggling with pain and inflammation we recommend our CBDA Oil or our CBD+CBDA Blend.

Insomniacs rejoice! For those having difficulty falling asleep, getting the right amount of sleep, or waking up in the middle of the night, we may have a solution. Our vanilla-flavored CBN Oil may be the ticket to the sweetest of dreams.

And of course, if you’re not quite sure if your other half has tried CBD products, we have the perfect CBD gift for you. For those first-timers out there, we recommend taking a test run with our Daily 25 vanilla flavored CBD. It makes a great introductory product and CBD gift for everyone!

In addition to these lovely CBD gifts, we offer smaller 15ml sizes in CBG Olive Oil, Daily 50 CBD Vanilla, and Daily 100 CBD Olive Oil.

What Goes into Myriam’s Hemp Products?

At Myriam’s Hemp, all our products are made with all-natural ingredients and premium hemp extract. Formulated for maximum absorption and efficacy, our full spectrum hemp oil boasts a full range of phytocannabinoids, beneficial terpenes, and flavonoids. We are proud to say that our products are rich in CBD and lab-tested for purity and safety. At Myriam’s Hemp we go the extra mile to make sure our products have everything you need, and nothing you don’t. Every product is completely vegan friendly, and free of wheat and sugar.

Purchase Your CBD for Valentine’s Day from Myriam’s Hemp

Myriam’s Hemp is a family-oriented, family-owned, and family-operated manufacturer of CBD and other hemp-derived products. We work alongside those we care about the most and aim to let this sense of caring permeate into the relationships we build with our customers. Having experienced firsthand the impact that disease can have on a family, we understand how having access to the right products can make all the difference. We truly are a customer-first company, and we work hard to keep it that way. Purchase premium CBD oil from Myriam’s Hemp today and experience the caring approach we take with all our customers and the benefits associated with full spectrum CBD.

CBD Gummies

CBD Gummies

CBD Gummies and Their Benefits

CBD gummies have become a wildly popular choice for those seeking to enjoy the natural components of CBD without experiencing the intoxicating effects of THC in marijuana. They provide a convenient method for consuming CBD and don’t require any equipment or stringent storage conditions – you can eat them at home or on the go to experience a myriad of benefits. But perhaps the most important aspect is the benefits that gummies offer over other methods of CBD use. Either way, CBD gummies are a great option that can suit most anyone’s needs.

CBD Gummies

What Are CBD Gummies?

CBD is extracted from hemp plants in oil form before it is processed into a wide variety of products such as capsules, lotions, tinctures, vape oils, and of course, gummies. While the method of consumption varies based on personal preference, CBD gummies are popular because they resemble candy and can be paired with various flavors to make them even more desirable to eat. CBD gummies can be made into all shapes and sizes such as gummy bears, drops, sugary rings, or other popular shapes. They vary in potency and there are numerous options to provide you with the right strength for your needs.

What Benefits Do CBD Gummies Provide?

Many people want to take advantage of the natural properties of cannabis, but not everyone wants to get high. CBD gummies offer many advantages over other forms of cannabis, and over other forms of CBD too. Some of the most common reasons why people choose CBD gummies include:

Precision. CBD gummies are manufactured to have the exact same dose of CBD in each one. This makes it very easy to measure how much you consume.

More discreet. Instead of smoking or vaping, CBD gummies can be eaten inconspicuously whether you’re at home or in a public setting.

Better tasting. When it tastes like candy, there’s no bad taste left behind. Some people find that CBD drops can have an unpleasant taste, but CBD gummies are delicious.

Convenient. No setup means no stress. Just pop one and enjoy the natural anti-stress benefits as you continue with your day.

Long-lasting. Compared to smoking or vaping, eating CBD gummies enables the active ingredients to last longer, giving you more relief.

Improved focus. Many have found that their use of CBD gummies has provided them with a better ability to focus on their daily tasks such as studying or working.

Zero lung irritation. If smoking isn’t your thing, gummies provide an excellent way to enjoy CBD without any lung irritation, coughing, or shortness of breath.

At Myriam’s Hemp, we believe that quality matters, and we strive to bring you the best CBD products available on the market. All of our products are made using 100% natural ingredients, don’t contain sugar or wheat, and provide a vegan friendly advantage. Our team understands the benefits of CBD and how it can create real change in terms of health and wellness. We want to continue to bring hope to those suffering through the negativity of pain and stress and provide relief through alternative, natural medicine. Experience the CBD difference with Myriam’s Hemp. CBD Gummies are coming soon!

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